Major congenital defects. Relevant risk factors. Cienfuegos. 2000-2005.

• Main Authors: Vivian Vázquez Martínez (Author), Cristóbal Torres González (Author), Gabriel González Jiménez (Author), Yobadis Hernández del Sol (Author), Ana López Rodríguez del Rey (Author), Gladis Barberis Pérez (Author)
• Format: Book
• Published: Centro Provincial de Información de Ciencias Médicas. Cienfuegos, 2008-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

<p><strong>Background:</strong> Major congenital defects have an impact on perinatal mortality and morbidity with economic and social consequences. <strong><br />Objective:</strong> To determine the relevant risk factors linked to the occurrence of congenital defects in Cienfuegos between 2000 and 2005. <strong><br />Methods:</strong> A case-control study was carried out. Women with fetus or newborns with major congenital defects formed the case group (255) while the control group consisted of a similar number of healthy children selected each year by a randomized simple sample. The variables gathered by the Cuban Congenital Defects Records were studied. Chi-Square method was used with 95% of accuracy and a reliance rate of 95%; logistic regression was used with the Wald test. <strong><br />Results:</strong> There was a predominance of Central Nervous System defects (28, 6%). The most relevant risk factors were a history of congenital defects, smoking habits, and acute infection during the first three months, as well as belong to the third birth on. <strong><br />Conclusion:</strong> The most clinical relevant risks factors were the congenital defect history and the acute infection during the firs three months.</p>

Item Description

1727-897X