Study of the Acidic, Basic, and Thermal Degradation Kinetics of Three Antihypertensive Drugs-Individually and in Combination

• Egile Nagusiak: Nebojša Mandić-Kovacević (Egilea), Irena Kasagić-Vujanović (Egilea), Biljana Gatarić (Egilea), Ranko Škrbić (Egilea), Ana Popović Bijelić (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2024-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background/Objectives: The importance of fixed-dose combinations (FDCs) for the treatment of hypertension is well established. However, from a stability perspective, FDCs present a challenge since the degradation of one active pharmaceutical ingredient (API) can be affected by the presence of anothe...