Genetics of Endometrial Cancers

• Main Authors: Tsuyoshi Okuda (Author), Akihiko Sekizawa (Author), Yuditiya Purwosunu (Author), Masaaki Nagatsuka (Author), Miki Morioka (Author), Masaki Hayashi (Author), Takashi Okai (Author)
• Format: Book
• Published: Hindawi Limited, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endometrial cancers exhibit a different mechanism of tumorigenesis and progression depending on histopathological and clinical types. The most frequently altered gene in estrogen-dependent endometrioid endometrial carcinoma tumors is PTEN. Microsatellite instability is another important genetic even...