Ciprofloxacin and pegylated G-CSF combined therapy mitigates brain hemorrhage and mortality induced by ionizing irradiation

• Автори: Juliann G. Kiang (Автор), Georgetta Cannon (Автор), Matthew G. Olson (Автор), Min Zhai (Автор), Akeylah K. Woods (Автор), Feng Xu (Автор), Bin Lin (Автор), Xianghong Li (Автор), Lisa Hull (Автор), Suping Jiang (Автор), Mang Xiao (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2023-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

IntroductionBrain hemorrhage was found between 13 and 16 days after acute whole-body 9.5 Gy 60Co-γ irradiation (IR). This study tested countermeasures mitigating brain hemorrhage and increasing survival from IR. Previously, we found that pegylated G-CSF therapy (PEG) (i.e., Neulasta®, an FDA-approve...