Age-Dependent Anti-migraine Effects of Valproic Acid and Topiramate in Rats
Background: Valproic acid (VPA) and topiramate (TPM), initially developed as antiepileptics, are approved for migraine prophylaxis in adults but not children. The differences in their antimigraine mechanism(s) by age remain unclear.Methods: A migraine model induced by intra-cisternal (i.c.) capsaici...
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Main Authors: | Pokai Huang (Author), Ping-Hung Kuo (Author), Ming Tatt Lee (Author), Lih-Chu Chiou (Author), Pi-Chuan Fan (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2018-09-01T00:00:00Z.
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