Nicotinic acetylcholine receptor subunit variants are associated with blood pressure; findings in the Old Order Amish and replication in the Framingham Heart Study

• Main Authors: Ott Sandy (Author), Ramachandran Vasan (Author), Wang Ying (Author), Damcott Coleen M (Author), Mitchell Braxton D (Author), Rutherford Sue (Author), McArdle Patrick F (Author), Chang Yen-Pei C (Author), Levy Daniel (Author), Steinle Nanette (Author)
• Format: Book
• Published: BMC, 2008-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Systemic blood pressure, influenced by both genetic and environmental factors, is regulated via sympathetic nerve activity. We assessed the role of genetic variation in three subunits of the neuromuscular nicotinic acetylcholine rece...