Tanshinone IIA: A Review of its Anticancer Effects

Tanshinone IIA (Tan IIA) is a pharmacologically lipophilic active constituent isolated from the roots and rhizomes of the Chinese medicinal herb Salvia miltiorrhiza Bunge (Danshen). Tan IIA is currently used in China and other neighboring countries to treat patients with cardiovascular system, diabe...

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Main Authors: Zhong‐ying Fang (Author), Miao Zhang (Author), Jia-ning Liu (Author), Xue Zhao (Author), Yong-qing Zhang (Author), Lei Fang (Author)
Format: Book
Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Zhong‐ying Fang  |e author 
700 1 0 |a Zhong‐ying Fang  |e author 
700 1 0 |a Miao Zhang  |e author 
700 1 0 |a Jia-ning Liu  |e author 
700 1 0 |a Xue Zhao  |e author 
700 1 0 |a Yong-qing Zhang  |e author 
700 1 0 |a Lei Fang  |e author 
700 1 0 |a Lei Fang  |e author 
245 0 0 |a Tanshinone IIA: A Review of its Anticancer Effects 
260 |b Frontiers Media S.A.,   |c 2021-01-01T00:00:00Z. 
500 |a 1663-9812 
500 |a 10.3389/fphar.2020.611087 
520 |a Tanshinone IIA (Tan IIA) is a pharmacologically lipophilic active constituent isolated from the roots and rhizomes of the Chinese medicinal herb Salvia miltiorrhiza Bunge (Danshen). Tan IIA is currently used in China and other neighboring countries to treat patients with cardiovascular system, diabetes, apoplexy, arthritis, sepsis, and other diseases. Recently, it was reported that tan IIA could have a wide range of antitumor effects on several human tumor cell lines, but the research of the mechanism of tan IIA is relatively scattered in cancer. This review aimed to summarize the recent advances in the anticancer effects of tan IIA and to provide a novel perspective on clinical use of tan IIA. 
546 |a EN 
690 |a Salvia miltiorrhiza 
690 |a tanshinone IIA 
690 |a anticancer 
690 |a mechanism 
690 |a traditional Chinese medicine 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Frontiers in Pharmacology, Vol 11 (2021) 
787 0 |n https://www.frontiersin.org/articles/10.3389/fphar.2020.611087/full 
787 0 |n https://doaj.org/toc/1663-9812 
856 4 1 |u https://doaj.org/article/571a00ccc3894e96a3119d03414f39ac  |z Connect to this object online.