Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates

• Hauptverfasser: Luca Piemontese (Verfasst von), Daniel Tomás (Verfasst von), Asha Hiremathad (Verfasst von), Vito Capriati (Verfasst von), Emanuel Candeias (Verfasst von), Sandra M. Cardoso (Verfasst von), Sílvia Chaves (Verfasst von), M. Amélia Santos (Verfasst von)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

A new series of multifunctional hybrids, based on the structure of the donepezil (DNP) drug, have been developed and evaluated as potential anti Alzheimer's disease (AD) agents. The rationale of this study was the conjugation of a benzylpiperidine/benzylpiperazine moiety with derivatives of bio...