Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates

• Κύριοι συγγραφείς: Luca Piemontese (Συγγραφέας), Daniel Tomás (Συγγραφέας), Asha Hiremathad (Συγγραφέας), Vito Capriati (Συγγραφέας), Emanuel Candeias (Συγγραφέας), Sandra M. Cardoso (Συγγραφέας), Sílvia Chaves (Συγγραφέας), M. Amélia Santos (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

A new series of multifunctional hybrids, based on the structure of the donepezil (DNP) drug, have been developed and evaluated as potential anti Alzheimer's disease (AD) agents. The rationale of this study was the conjugation of a benzylpiperidine/benzylpiperazine moiety with derivatives of bio...