Allosterically activating SHP2 by oleanolic acid inhibits STAT3-Th17 axis for ameliorating colitis
Src homology 2 domain-containing tyrosine phosphatase 2 (SHP2) is an essential tyrosine phosphatase that is pivotal in regulating various cellular signaling pathways such as cell growth, differentiation, and survival. The activation of SHP2 has been shown to have a therapeutic effect in colitis and...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2024-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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