Spectrophotometric method for simultaneous estimation of atenolol in combination with losartan potassium and hydrochlorothiazide in bulk and tablet formulation

Aim : To develop a simple, accurate, rapid and precise UV spectrophotometric method for the estimation of atenolol in combination with losartan potassium and hydrochlorothiazide. Materials and Methods : The method employs formation and solving simultaneous equation using 251.60 nm and 224.20 nm for...

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Bibliographic Details
Main Authors: Sanjay Bari (Author), Shital Sathe (Author), Pritam Jain (Author), Sanjay Surana (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2010-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Sanjay Bari  |e author 
700 1 0 |a Shital Sathe  |e author 
700 1 0 |a Pritam Jain  |e author 
700 1 0 |a Sanjay Surana  |e author 
245 0 0 |a Spectrophotometric method for simultaneous estimation of atenolol in combination with losartan potassium and hydrochlorothiazide in bulk and tablet formulation 
260 |b Wolters Kluwer Medknow Publications,   |c 2010-01-01T00:00:00Z. 
500 |a 0975-7406 
500 |a 0976-4879 
500 |a 10.4103/0975-7406.72144 
520 |a Aim : To develop a simple, accurate, rapid and precise UV spectrophotometric method for the estimation of atenolol in combination with losartan potassium and hydrochlorothiazide. Materials and Methods : The method employs formation and solving simultaneous equation using 251.60 nm and 224.20 nm for losartan potassium and atenolol, 224.20 and 271.60 for atenolol and hydrochlorothiazide as two analytical wavelengths, using methanol water as a solvent. Results and Conclusion : The linearity was observed in the concentration range of 5-30 μg/ml (r=0.9991) for losratan pottassium, 2 - 12 μg/ml (r = 0.9995) for atenolol and 2 - 14 μg/ml (r = 0.9993) for hydrochlorothiazide. The results of the method were validated statistically and by recovery studies. 
546 |a EN 
690 |a Atenolol 
690 |a hydrochlorothiazide 
690 |a losartan potassium 
690 |a spectrophotometric method 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
690 |a Analytical chemistry 
690 |a QD71-142 
655 7 |a article  |2 local 
786 0 |n Journal of Pharmacy and Bioallied Sciences, Vol 2, Iss 4, Pp 372-375 (2010) 
787 0 |n http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2010;volume=2;issue=4;spage=372;epage=375;aulast=Bari 
787 0 |n https://doaj.org/toc/0975-7406 
787 0 |n https://doaj.org/toc/0976-4879 
856 4 1 |u https://doaj.org/article/57b6b989a8ab4e709e6631d09a832e29  |z Connect to this object online.