Spectrophotometric method for simultaneous estimation of atenolol in combination with losartan potassium and hydrochlorothiazide in bulk and tablet formulation
Aim : To develop a simple, accurate, rapid and precise UV spectrophotometric method for the estimation of atenolol in combination with losartan potassium and hydrochlorothiazide. Materials and Methods : The method employs formation and solving simultaneous equation using 251.60 nm and 224.20 nm for...
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Wolters Kluwer Medknow Publications,
2010-01-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_57b6b989a8ab4e709e6631d09a832e29 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Sanjay Bari |e author |
700 | 1 | 0 | |a Shital Sathe |e author |
700 | 1 | 0 | |a Pritam Jain |e author |
700 | 1 | 0 | |a Sanjay Surana |e author |
245 | 0 | 0 | |a Spectrophotometric method for simultaneous estimation of atenolol in combination with losartan potassium and hydrochlorothiazide in bulk and tablet formulation |
260 | |b Wolters Kluwer Medknow Publications, |c 2010-01-01T00:00:00Z. | ||
500 | |a 0975-7406 | ||
500 | |a 0976-4879 | ||
500 | |a 10.4103/0975-7406.72144 | ||
520 | |a Aim : To develop a simple, accurate, rapid and precise UV spectrophotometric method for the estimation of atenolol in combination with losartan potassium and hydrochlorothiazide. Materials and Methods : The method employs formation and solving simultaneous equation using 251.60 nm and 224.20 nm for losartan potassium and atenolol, 224.20 and 271.60 for atenolol and hydrochlorothiazide as two analytical wavelengths, using methanol water as a solvent. Results and Conclusion : The linearity was observed in the concentration range of 5-30 μg/ml (r=0.9991) for losratan pottassium, 2 - 12 μg/ml (r = 0.9995) for atenolol and 2 - 14 μg/ml (r = 0.9993) for hydrochlorothiazide. The results of the method were validated statistically and by recovery studies. | ||
546 | |a EN | ||
690 | |a Atenolol | ||
690 | |a hydrochlorothiazide | ||
690 | |a losartan potassium | ||
690 | |a spectrophotometric method | ||
690 | |a Pharmacy and materia medica | ||
690 | |a RS1-441 | ||
690 | |a Analytical chemistry | ||
690 | |a QD71-142 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Journal of Pharmacy and Bioallied Sciences, Vol 2, Iss 4, Pp 372-375 (2010) | |
787 | 0 | |n http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2010;volume=2;issue=4;spage=372;epage=375;aulast=Bari | |
787 | 0 | |n https://doaj.org/toc/0975-7406 | |
787 | 0 | |n https://doaj.org/toc/0976-4879 | |
856 | 4 | 1 | |u https://doaj.org/article/57b6b989a8ab4e709e6631d09a832e29 |z Connect to this object online. |