Kinomic profiling of glioblastoma cells reveals PLCG1 as a target in restricted glucose
Abstract Background For glioblastoma (GBM) treatments to be effective in vivo, understanding the effects of the tumor microenvironment is imperative. In traditional cell culture conditions, glucose concentrations do not model physiologic levels, nor the diminished concentrations found in tumor niche...
Saved in:
Main Authors: | Kiera Walker (Author), Nathaniel H. Boyd (Author), Joshua C. Anderson (Author), Christopher D. Willey (Author), Anita B. Hjelmeland (Author) |
---|---|
Format: | Book |
Published: |
BMC,
2018-06-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Kinome profiling of cholangiocarcinoma organoids reveals potential druggable targets that hold promise for treatment stratification
by: Ruby Lieshout, et al.
Published: (2022) -
Kinome-wide polypharmacology profiling of small molecules by multi-task graph isomorphism network approach
by: Lingjie Bao, et al.
Published: (2023) -
PLCG2 and IFNAR1: The Potential Biomarkers Mediated by Immune Infiltration and Osteoclast Differentiation of Ankylosing Spondylitis in the Peripheral Blood
by: Bo Han, et al.
Published: (2024) -
Deep phosphoproteome analysis of Schistosoma mansoni leads development of a kinomic array that highlights sex-biased differences in adult worm protein phosphorylation.
by: Natasha L Hirst, et al.
Published: (2020) -
The kinome, cyclins and cyclin-dependent kinases of pituitary adenomas, a look into the gene expression profile among tumors from different lineages
by: Keiko Taniguchi-Ponciano, et al.
Published: (2022)