Phosphodiesterases S-sulfhydration contributes to human skeletal muscle function.

• Main Authors: Valentina Vellecco (Author), Elisabetta Panza (Author), Sofia-Iris Bibli (Author), Gian Marco Casillo (Author), Federica Raucci (Author), Onorina Laura Manzo (Author), Martina Smimmo (Author), Romolo Villani (Author), Maria Rosaria Cavezza (Author), Ingrid Fleming (Author), Roberta d'Emmanuele di Villa Bianca (Author), Francesco Maione (Author), Giuseppe Cirino (Author), Mariarosaria Bucci (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The increase in intracellular calcium is influenced by cyclic nucleotides (cAMP and cGMP) content, which rating is governed by phosphodiesterases (PDEs) activity.Despite it has been demonstrated a beneficial effect of PDEs inhibitors in different pathological conditions involving SKM, not much is kn...