CTLA-4 Polymorphisms in Patients with IgA Nephropathy Correlate with Proteinuria

• Autores principales: Marius Jacob (Autor), Kim Ohl (Autor), Tannaz Goodarzi (Autor), Sigrid Harendza (Autor), Thomas Eggermann (Autor), Christina Fitzner (Autor), Ralf-Dieter Hilgers (Autor), Anna Bolte (Autor), Jürgen Floege (Autor), Thomas Rauen (Autor), Klaus Tenbrock (Autor)
• Formato: Libro
• Publicado: Karger Publishers, 2018-03-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Background/Aims: IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis and still constitutes one of the most important causes of end-stage renal disease. Abnormal T cell responses may play a role in IgAN pathogenesis. Co-stimulatory molecules such as cytotoxic T lymphocyte-ass...