Synthesis of Functionalized <i>N</i>-(4-Bromophenyl)furan-2-carboxamides via Suzuki-Miyaura Cross-Coupling: Anti-Bacterial Activities against Clinically Isolated Drug Resistant <i>A. baumannii</i>, <i>K. pneumoniae</i>, <i>E. cloacae</i> and MRSA and Its Validation via a Computational Approach
<i>N</i>-(4-bromophenyl)furan-2-carboxamide (<b>3</b>) was synthesized by the reaction furan-2-carbonyl chloride (<b>1</b>) and 4-bromoaniline (<b>2</b>) in the presence of Et<sub>3</sub>N in excellent yields of 94%. The carboxamide (<b&...
Saved in:
Main Authors: | Ayesha Siddiqa (Author), Muhammad Zubair (Author), Muhammad Bilal (Author), Nasir Rasool (Author), Muhammad Usman Qamar (Author), Aqsa Khalid (Author), Gulraiz Ahmad (Author), Muhammad Imran (Author), Sajid Mahmood (Author), Ghulam Abbas Ashraf (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2022-07-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Synthesis of Novel (<i>S</i>)-3-(1-Aminoethyl)-8-pyrimidinyl-2-phenylisoquinolin-1(2<i>H</i>)-ones by Suzuki-Miyaura Coupling and Their Cell Toxicity Activities
by: Ok Kyoung Choi, et al.
Published: (2022) -
Facile Synthesis of <i>N</i>-(4-Bromo-3-methylphenyl)pyrazine-2-carboxamide Derivatives, Their Antibacterial Activities against Clinically Isolated XDR <i>S. Typhi</i>, Alkaline Phosphatase Inhibitor Activities, and Docking Studies
by: Abdul Hannan Khan, et al.
Published: (2024) -
Absence of <i>mgrB</i> Alleviates Negative Growth Effects of Colistin Resistance in <i>Enterobacter cloacae</i>
by: Jessie E. Wozniak, et al.
Published: (2020) -
<i>In vitro</i> phytochemical and antimicrobial screening of <i>Thymus linearis</i>
by: Attiqa Naz, et al.
Published: (2015) -
Antimicrobial Resistance and Biofilms Underlying Catheter-Related Bloodstream Coinfection by <i>Enterobacter cloacae</i> Complex and <i>Candida parapsilosis</i>
by: Matúš Štefánek, et al.
Published: (2022)