Aldosterone Synthesis and Cytokine Production in Human Peripheral Blood Mononuclear Cells

• Main Authors: Ryuzea Miura (Author), Kazufumi Nakamura (Author), Daiji Miura (Author), Aya Miura (Author), Kenichi Hisamatsu (Author), Masahito Kajiya (Author), Katsushi Hashimoto (Author), Satoshi Nagase (Author), Hiroshi Morita (Author), Kengo Fukushima Kusano (Author), Tetsuro Emori (Author), Kazuhiko Ishihara (Author), Tohru Ohe (Author)
• Format: Book
• Published: Elsevier, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previously, we reported that spironolactone reduced cytokine production in cultured human peripheral blood mononuclear cells (PBMCs) with angiotensin (Ang) II stimulation. To address the mechanisms underlying this effect, we examined the contribution of aldosterone to cytokine production in cultured...