Medically resistant juvenile myasthenia gravis following thymectomy: Role for FDG PET/CT

Thymectomy is part of a multimodal treatment strategy for juvenile myasthenia gravis. Symptoms that persist following thymectomy may be due to residual or ectopic thymic tissue. We report the use of FDG PET/CT to locate residual thymic tissue following thymectomy in a 10 year old girl with acetylcho...

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Main Authors: Florence Ngu (Author), Michael Cardamone (Author), Dylan Wanaguru (Author), Bruce Currie (Author), Eva Alina Wegner (Author), Ian Andrews (Author), Walter Haindl (Author)
Format: Book
Published: Elsevier, 2020-08-01T00:00:00Z.
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Summary:Thymectomy is part of a multimodal treatment strategy for juvenile myasthenia gravis. Symptoms that persist following thymectomy may be due to residual or ectopic thymic tissue. We report the use of FDG PET/CT to locate residual thymic tissue following thymectomy in a 10 year old girl with acetylcholine-receptor-antibody-positive myasthenia gravis, who remained refractory to medical therapy. The patient subsequently underwent completion thymectomy with improvement but not remission of her condition.
Item Description:2213-5766
10.1016/j.epsc.2020.101494