Aliskiren, a Direct Renin Inhibitor, Improves Vascular Endothelial Function in Patients on Hemodialysis Independent of Antihypertensive Effect ∼ a Pilot Study∼

• Main Authors: Hidekazu Moriya (Author), Shuzo Kobayashi (Author), Takayasu Ohtake (Author), Daimu Tutumi (Author), Yasuhiro Mochida (Author), Kunihiro Ishioka (Author), Machiko Oka (Author), Kyoko Maesato (Author), Sumi Hidaka (Author), Shosaku Nomura (Author)
• Format: Book
• Published: Karger Publishers, 2013-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: Aliskiren inhibits the first step in the renin-angiotensin system (RAS) and recently has been shown to modulate vascular diseases via RAS-dependent and independent pathways. This study aimed to determine the effect of aliskiren-associated direct renin inhibition on endothelial function in pati...