Design, synthesis and biological evaluation of novel N-phosphorylated and O-phosphorylated tacrine derivatives as potential drugs against Alzheimer's disease
In this work, we designed, synthesised and biologically investigated a novel series of 14 N- and O-phosphorylated tacrine derivatives as potential anti-Alzheimer's disease agents. In the reaction of 9-chlorotacrine and corresponding diamines/aminoalkylalcohol we obtained diamino and aminoalkylh...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Taylor & Francis Group,
2022-12-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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