Chimeric Drug Design with a Noncharged Carrier for Mitochondrial Delivery

• Autores principales: Consuelo Ripoll (Autor), Pilar Herrero-Foncubierta (Autor), Virginia Puente-Muñoz (Autor), M. Carmen Gonzalez-Garcia (Autor), Delia Miguel (Autor), Sandra Resa (Autor), Jose M. Paredes (Autor), Maria J. Ruedas-Rama (Autor), Emilio Garcia-Fernandez (Autor), Mar Roldan (Autor), Susana Rocha (Autor), Herlinde De Keersmaecker (Autor), Johan Hofkens (Autor), Miguel Martin (Autor), Juan M. Cuerva (Autor), Angel Orte (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2021-02-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Recently, it was proposed that the thiophene ring is capable of promoting mitochondrial accumulation when linked to fluorescent markers. As a noncharged group, thiophene presents several advantages from a synthetic point of view, making it easier to incorporate such a side moiety into different mole...