Effect of hypoxia on progesterone production by cultured bovine early and mid luteal cells

• Main Authors: Hiroki HASEGAWA (Author), Ryo NISHIMURA (Author), Masamichi YAMASHITA (Author), Takeshi YAMAGUCHI (Author), Mitsugu HISHINUMA (Author), Kiyoshi OKUDA (Author)
• Format: Book
• Published: The Society for Reproduction and Development, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A major role of the corpus luteum (CL) is to produce progesterone (P4). The CL has immature vasculature shortly after ovulation, suggesting it exists under hypoxic conditions. To elucidate the mechanism involved in regulation of luteal cell function during CL development, we compared the effect of h...