Suppression of medulloblastoma lesions by forced migration of preneoplastic precursor cells with intracerebellar administration of the chemokine Cxcl3
Medulloblastoma (MB), tumor of the cerebellum, remains a leading cause of cancer-related mortality in childhood.We previously showed, in a mouse model of spontaneous MB (Ptch1+/-/Tis21-/-), that a defect of the migration of cerebellar granule neuron precursor cells (GCPs) correlates with an increase...
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Main Authors: | Manuela Ceccarelli (Author), Laura Micheli (Author), Felice Tirone (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2016-12-01T00:00:00Z.
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