Novel ion exchange resin-based combination drug-delivery system for treatment of gastro esophageal reflux diseases

• Main Authors: Mangesh Ramesh Bhalekar (Author), Nitin Madhukar Kadam (Author), Nilam Hindurao Patil (Author), Nitin Somnath Gawale (Author), Ashwini Madgulkar (Author)
• Format: Book
• Published: Universidade de São Paulo, 2010-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study involves preparation and characterization of a combination tablet of ranitidine in immediate release form and domperidone in sustained release form, using ion exchange resins. Ranitidine lowers acid secretion, while domperidone release over a prolonged period improves gastric motil...