Inhibitors of recombinant protein-tyrosine phosphatase 1B (PTP1B) from Khaya senegalensis: Towards a strategic target for therapeutic intervention in trypanosomiasis

• প্রধান লেখক: Fatima Amin Adamude (লেখক), Ikenna Nnamdi Ezeaku (লেখক), Abraham Ehinomhen Ubhenin (লেখক), Ifeanyi Peter Onyeka (লেখক), Ahmad Adamu Ambi (লেখক), Ikechukwu Robert Uroko (লেখক), Emeka John Dingwoke (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2022-08-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background: Tyrosine dephosphorylation, catalyzed by protein-tyrosine phosphatase (PTP), prevents trypanosome differentiation to a procyclic form that lacks diverse mechanisms for survival within the mammalian host's bloodstream. Thus, differentiation to a procyclic form in the mammalian host&#...