Inhibitors of recombinant protein-tyrosine phosphatase 1B (PTP1B) from Khaya senegalensis: Towards a strategic target for therapeutic intervention in trypanosomiasis

• Prif Awduron: Fatima Amin Adamude (Awdur), Ikenna Nnamdi Ezeaku (Awdur), Abraham Ehinomhen Ubhenin (Awdur), Ifeanyi Peter Onyeka (Awdur), Ahmad Adamu Ambi (Awdur), Ikechukwu Robert Uroko (Awdur), Emeka John Dingwoke (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2022-08-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Background: Tyrosine dephosphorylation, catalyzed by protein-tyrosine phosphatase (PTP), prevents trypanosome differentiation to a procyclic form that lacks diverse mechanisms for survival within the mammalian host's bloodstream. Thus, differentiation to a procyclic form in the mammalian host&#...