Inhibitors of recombinant protein-tyrosine phosphatase 1B (PTP1B) from Khaya senegalensis: Towards a strategic target for therapeutic intervention in trypanosomiasis

• Κύριοι συγγραφείς: Fatima Amin Adamude (Συγγραφέας), Ikenna Nnamdi Ezeaku (Συγγραφέας), Abraham Ehinomhen Ubhenin (Συγγραφέας), Ifeanyi Peter Onyeka (Συγγραφέας), Ahmad Adamu Ambi (Συγγραφέας), Ikechukwu Robert Uroko (Συγγραφέας), Emeka John Dingwoke (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2022-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Background: Tyrosine dephosphorylation, catalyzed by protein-tyrosine phosphatase (PTP), prevents trypanosome differentiation to a procyclic form that lacks diverse mechanisms for survival within the mammalian host's bloodstream. Thus, differentiation to a procyclic form in the mammalian host&#...