Inhibitors of recombinant protein-tyrosine phosphatase 1B (PTP1B) from Khaya senegalensis: Towards a strategic target for therapeutic intervention in trypanosomiasis

• Asıl Yazarlar: Fatima Amin Adamude (Yazar), Ikenna Nnamdi Ezeaku (Yazar), Abraham Ehinomhen Ubhenin (Yazar), Ifeanyi Peter Onyeka (Yazar), Ahmad Adamu Ambi (Yazar), Ikechukwu Robert Uroko (Yazar), Emeka John Dingwoke (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2022-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background: Tyrosine dephosphorylation, catalyzed by protein-tyrosine phosphatase (PTP), prevents trypanosome differentiation to a procyclic form that lacks diverse mechanisms for survival within the mammalian host's bloodstream. Thus, differentiation to a procyclic form in the mammalian host&#...