Rubidium Chloride Targets Jnk/p38-Mediated NF-κB Activation to Attenuate Osteoclastogenesis and Facilitate Osteoblastogenesis

• Главные авторы: Zhengxiao Ouyang (Автор), Qianli Huang (Автор), Bin Liu (Автор), Hong Wu (Автор), Tang Liu (Автор), Yong Liu (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Предметы: article
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The unbalanced crosstalk between osteoclasts and osteoblasts could lead to disruptive bone homeostasis. Herein, we investigated the therapeutic effects of rubidium chloride (RbCl) on ovariectomized (OVX) and titanium (Ti) particle-induced calvaria osteolysis mouse models, showing that non-toxic RbCl...