Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells

• Main Authors: Pintado Belen (Author), Moreira Pedro (Author), Fernandez-Gonzalez Raul (Author), Pericuesta Eva (Author), Ramírez Miguel A (Author), Gutierrez-Adan Alfonso (Author)
• Format: Book
• Published: BMC, 2006-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>In the mouse, culture of embryonic stem (ES) cells may decrease their pluripotency and give rise to foetal abnormalities in recipient embryos. These abnormalities are frequently associated with both, chromosome abnormalities or epige...