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Histopathological dimensions differ between aganglionic and ganglionic bowel wall in children with Hirschsprung's disease

Highlights • To confirm ganglionic bowel wall in Hirschsprung's disease, intra-operative frozen biopsy samples are required. This means a prolonged anesthesia time and a more immediate diagnostic method is warranted. • Muscle layers' thicknesses differ between aganglionic and ganglionic bo...

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Main Authors: Christina Graneli (Author), Sofia Patarroyo (Author), Rodrigo Munoz Mitev (Author), David Gisselsson (Author), Emilia Gottberg (Author), Tobias Erlöv (Author), Tomas Jansson (Author), Kristine Hagelsteen (Author), Magnus Cinthio (Author), Pernilla Stenström (Author)
Format: Book
Published: BMC, 2022-12-01T00:00:00Z.
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Summary:Highlights • To confirm ganglionic bowel wall in Hirschsprung's disease, intra-operative frozen biopsy samples are required. This means a prolonged anesthesia time and a more immediate diagnostic method is warranted. • Muscle layers' thicknesses differ between aganglionic and ganglionic bowel walls in children with Hirshsprung's disease. These findings could be transferred to instant imaging techniques. • See the attached Supplementary Figure 2
Item Description:10.1186/s12887-022-03792-3
1471-2431

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