Use of topical imiquimod in the treatment of VIN: a case report and review of the literature

Vulvar intraepithelial neoplasia (VIN) is a premalignant disease of the vulvar squamous epithelium. Standard treatment for VIN lesions is surgical excision. Alternative therapeutic options for conservative treatment have been sought by patients to prevent disfigurement and to preserve sexual functio...

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Main Authors: Chelsea Grimes, BS, MS (Author), Cheri Cunningham, BS (Author), Michael Lee, MD (Author), Andrea Murina, MD (Author)
Format: Book
Published: Wolters Kluwer, 2016-03-01T00:00:00Z.
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100 1 0 |a Chelsea Grimes, BS, MS  |e author 
700 1 0 |a Cheri Cunningham, BS  |e author 
700 1 0 |a Michael Lee, MD  |e author 
700 1 0 |a Andrea Murina, MD  |e author 
245 0 0 |a Use of topical imiquimod in the treatment of VIN: a case report and review of the literature 
260 |b Wolters Kluwer,   |c 2016-03-01T00:00:00Z. 
500 |a 2352-6475 
500 |a 10.1016/j.ijwd.2015.12.007 
520 |a Vulvar intraepithelial neoplasia (VIN) is a premalignant disease of the vulvar squamous epithelium. Standard treatment for VIN lesions is surgical excision. Alternative therapeutic options for conservative treatment have been sought by patients to prevent disfigurement and to preserve sexual function. We present such a patient in whom topical imiquimod was used with a successful outcome. Imiquimod is effective in the treatment of VIN, as well as convenient, self-administered, and generally well tolerated. Keywords: vulvar intraepithelial neoplasia, Bowen's disease, squamous cell carcinoma in situ, imiquimod 
546 |a EN 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n International Journal of Women's Dermatology, Vol 2, Iss 1, Pp 35-38 (2016) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S2352647515000763 
787 0 |n https://doaj.org/toc/2352-6475 
856 4 1 |u https://doaj.org/article/59cab0e2acf04c9f9fd0dd26ed44d1a3  |z Connect to this object online.