Functional Role of P-Glycoprotein and Binding Protein Effect on the Placental Transfer of Lopinavir/Ritonavir in the Ex Vivo Human Perfusion Model
Aims. To study the influence of P-glycoprotein (P-glycoprotein, ABCB1, MDR1) function on placental transfer of lopinavir with ritonavir at different albumin concentrations. Methods. Cotyledons were perfused with lopinavir, ritonavir, and the internal control antipyrin, at various albumin concentrati...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Hindawi Limited,
2009-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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