IgG4 antibodies to the recombinant filarial antigen Wb-Bhp-1 decrease dramatically following treatment of lymphatic filariasis.

• Main Authors: Sarah E Greene (Author), Yuefang Huang (Author), Kurt C Curtis (Author), Christopher L King (Author), Peter U Fischer (Author), Gary J Weil (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Lymphatic filariasis (LF) is a neglected tropical disease and a major cause of chronic disability. Improved diagnostic tests are needed because of long-term persistence of anti-filarial antibodies or circulating filarial antigenemia after treatments that clear microfil...