Infectious events in kidney transplant recipients from deceased expanded criteria donors: a prospective cohort

• Main Authors: Sirlei Regina de Sousa (Author), Cassiane Dezoti da Fonseca (Author), Monica Taminato (Author), Maria de Fatima Fernandes Vattimo (Author), Angélica Gonçalves Silva Belasco (Author), Álvaro Francisco Lopes de Sousa (Author), Inês Fronteira (Author), Dulce Aparecida Barbosa (Author)
• Format: Book
• Published: SciELO.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1980-220X; 10.1590/1980-220x-reeusp-2021-0255
• Keywords: Infections; Kidney Transplantation; Transplants; Mortality; Survival rate; Public aspects of medicine; RA1-1270; Nursing; RT1-120; Mental healing; RZ400-408; Education (General); L7-991
• Source: Revista da Escola de Enfermagem da USP

ABSTRACT Objective: Analyze risk factors for infection in kidney transplant recipients from deceased expanded criteria donors (DECD) in the first two years of follow-up. Method: This is a prospective cohort study with 466 patients from DECD who underwent kidney transplantation in 2015 and 2016 in Brazil. A total of 551 events were recorded. The largest incidence of infectious events occurred in the first month after kidney transplantation. Cytomegalovirus infection was the most common infectious episode. Results: The incidence rate of infections was 57.1%. Among bacterial infections, only 4% were due to multidrug-resistant microorganisms. The death rate was 3.3% (15) patients. The main cause of death was infectious (73.3%). Hospitalization until the first infection (aOR:1.61), Number of infections in 1 year (aOR:40.16), and Cytomegalovirus infection (aOR:13.84) was risk factors for infection by multidrug resistant microorganisms (MDR). Conclusion: Infection incidence with MDR bacteria was high among kidney transplant recipients from DECD, and the main cause of death was infection. Survival was high among patients with infection.