Shikonin Induces ROS-Dependent Apoptosis Via Mitochondria Depolarization and ER Stress in Adult T Cell Leukemia/Lymphoma
Adult T cell leukemia/lymphoma (ATLL) is an aggressive T-cell malignancy that develops in some elderly human T-cell leukemia virus (HTVL-1) carriers. ATLL has a poor prognosis despite conventional and targeted therapies, and a new safe and efficient therapy is required. Here, we examined the anti-AT...
Saved in:
Main Authors: | Piyanard Boonnate (Author), Ryusho Kariya (Author), Seiji Okada (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2023-04-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Senescence Inducer Shikonin ROS-Dependently Suppressed Lung Cancer Progression
by: Hongming Zheng, et al.
Published: (2018) -
Condurango (Gonolobus condurango) Extract Activates Fas Receptor and Depolarizes Mitochondrial Membrane Potential to Induce ROS-dependent Apoptosis in Cancer Cells in vitro CE-treatment on HeLa: a ROS-dependent mechanism
by: Kausik Bishayee, et al.
Published: (2015) -
The anti-leukemia activity and mechanisms of shikonin: a mini review
by: Han Dong, et al.
Published: (2023) -
Shikonin impairs mitochondrial activity to selectively target leukemia cells
by: Alessia Roma, et al.
Published: (2022) -
Mitochondrial Delivery of Phenol Substructure Triggers Mitochondrial Depolarization and Apoptosis of Cancer Cells
by: Elena Gazzano, et al.
Published: (2018)