Antidepressant-like effect of aqueous extract from Rosa damascena in mice
Objective: Rosa damascena mill L (R. damascena) is an ornamental plant that has several therapeutic (such as sedative and hypnotic) effects. It also heals depression, grief, nervous stress and tension. In the present study we evaluated antidepressant-like effect of R. damascena using forced swimming...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | पुस्तक |
| प्रकाशित: |
Mashhad University of Medical Sciences,
2011-09-01T00:00:00Z.
|
| विषय: | |
| ऑनलाइन पहुंच: | Connect to this object online. |
| टैग: |
टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
|
| सारांश: | Objective: Rosa damascena mill L (R. damascena) is an ornamental plant that has several therapeutic (such as sedative and hypnotic) effects. It also heals depression, grief, nervous stress and tension. In the present study we evaluated antidepressant-like effect of R. damascena using forced swimming test (FST). Material and Methods: Three doses of aqueous extract (15, 60 and 90 mg/kg) was injected intraperitoneally. After 30 min of injection, immobility and swimming times were measured and compared with control (negative control) and imipramine (positive control). Results: The results showed that low dose (15mg/kg) of extract significantly increased swimming time and decreased immobility time. However, the two high doses of extract (60 and 90mg/kg) had no significant effect on these parameters. Conclusion: These results proposed antidepressant-like effect of low concentration of aqueous extract of R. damascena. |
|---|---|
| वस्तु वर्णन: | 2228-7930 2228-7949 |