Semi-automated analysis of HER2 immunohistochemistry in invasive breast carcinoma using whole slide images: utility for interpretation in clinical practice

• Main Authors: Chiu-Hsiang Connie Liao (Author), Nilay Bakoglu (Author), Emine Cesmecioglu (Author), Matthew Hanna (Author), Fresia Pareja (Author), Hannah Y. Wen (Author), Timothy M. D'Alfonso (Author), Edi Brogi (Author), Yukako Yagi (Author), Dara S. Ross (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human epidermal growth factor receptor 2 (HER2) gene amplification and subsequent protein overexpression is a strong prognostic and predictive biomarker in invasive breast carcinoma (IBC). ASCO/CAP recommended tests for HER2 assessment include immunohistochemistry (IHC) and/or in situ hybridization...