Transcriptomic Responses to Polymyxin B and Analogues in Human Kidney Tubular Cells
Polymyxins are last-line antibiotics for the treatment of Gram-negative 'superbugs'. However, nephrotoxicity can occur in up to 60% of patients administered intravenous polymyxins. The mechanisms underpinning nephrotoxicity remain unclear. To understand polymyxin-induced nephrotoxicity, hu...
Saved in:
Main Authors: | Mengyao Li (Author), Mohammad A. K. Azad (Author), Philip E. Thompson (Author), Kade D. Roberts (Author), Tony Velkov (Author), Yan Zhu (Author), Jian Li (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2023-02-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Polymyxin Induces Significant Transcriptomic Perturbations of Cellular Signalling Networks in Human Lung Epithelial Cells
by: Mengyao Li, et al.
Published: (2022) -
Synergistic Killing of Polymyxin B in Combination With the Antineoplastic Drug Mitotane Against Polymyxin-Susceptible and -Resistant Acinetobacter baumannii: A Metabolomic Study
by: Thien B. Tran, et al.
Published: (2018) -
Clinically Relevant Concentrations of Polymyxin B and Meropenem Synergistically Kill Multidrug-Resistant <i>Pseudomonas aeruginosa</i> and Minimize Biofilm Formation
by: Hasini Wickremasinghe, et al.
Published: (2021) -
Mechanisms Underlying Synergistic Killing of Polymyxin B in Combination with Cannabidiol against <i>Acinetobacter baumannii</i>: A Metabolomic Study
by: Maytham Hussein, et al.
Published: (2022) -
Thanatin and vinyl sulfide analogues as narrow spectrum antimicrobial peptides that synergise with polymyxin B
by: Oscar A. Shepperson, et al.
Published: (2024)