Changes of masseter muscle after mandible distraction osteogenesis in patients with Hemifacial microsomia: a retrospective study

• Main Authors: Wenqing Han (Author), Byeong Seop Kim (Author), Ziwei Zhang (Author), Xiaojun Chen (Author), Yingjie Yan (Author), Li Lin (Author), Yan Zhang (Author), Gang Chai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2296-2360; 10.3389/fped.2024.1453270
• Keywords: Hemifacial microsomia; masseter muscle; mandible distraction osteogenesis; CT; quantitative analysis; Pediatrics; RJ1-570
• Source: Frontiers in Pediatrics, Vol 12 (2024)

IntroductionMandible distraction osteogenesis (MDO) is widely used to reconstruct the mandible in patients with mild Hemifacial microsomia (HFM). However, the masseter's response to mandible distraction remains unclear.MethodsIn this study, we analyze the effect of the surgical intervention on masseter muscle by a retrospective analysis. The procedure consisted of a five-day latent period, a three-week distraction period, and a six-month consolidation period. CT data were manually segmented and measured with Mimics software before surgery, within 3 months, and more than 1 year postoperatively. Masseter volume, masseter length, masseter width, and mandible ramus height were measured and analyzed using paired t-test, Pearson, and Spearman correlation analysis.ResultsWe included 21 patients with HFM who underwent mandible distraction osteogenesis from 2015 to 2020. The masseter volume on the affected side increased immediately after surgery from (6,505.33 ± 3,671.95) mm3 to (10,194.60 ± 5638.79) mm3, but decreased to (8,148.38 ± 3,472.57) mm3 at the second follow-up correlated to mandible ramus height (r = 0.395, P = 0.038). A similar trend was observed in changes in masseter length. Symmetry and width of masseter muscle had no longitudinal statistical significance.DiscussionMasseter muscle involvement benefits from MDO in the short term. To achieve long-term efficacy, more attention should be paid to muscle reconstruction.