Antihyperlipidemic effect of Ficus dalhousiae miq. stem bark on Triton WR-1339 and high fat diet-induced hyperlipidemic rats
Ficus dalhousiae stem bark is used to treat cancer and hyperlipidemia in folklore practices. F. dalhousiae stem bark methanolic extract (250 and 500 mg/kg b. wt.) was evaluated for antihyperlipidemic activity in Triton WR-1339 and high fat diet-induced hyperlipidemic rats. F. dalhousiae extract sign...
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| Main Authors: | , , , |
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| Format: | Book |
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Faculty of Pharmacy, Cairo University,
2017-06-01T00:00:00Z.
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| Summary: | Ficus dalhousiae stem bark is used to treat cancer and hyperlipidemia in folklore practices. F. dalhousiae stem bark methanolic extract (250 and 500 mg/kg b. wt.) was evaluated for antihyperlipidemic activity in Triton WR-1339 and high fat diet-induced hyperlipidemic rats. F. dalhousiae extract significantly (P ⩽ 0.005) alter the serum TC, TG, LDL-C and HDL-C levels to near normal in Triton WR-1339 and high fat diet-induced hyperlipidemic rats. The liver total cholesterol and triglycerides were also significantly reduced after treatment with 250 and 500 mg/kg of F. dalhousiae. The result of this study indicates that F. dalhousiae has a significant potential to use as a natural antihyperlipidemic agent. |
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| Item Description: | 1110-0931 10.1016/j.bfopcu.2016.10.003 |