LCâUV/MS quality analytics of paediatric artemether formulations

• Main Authors: Kirsten Vandercruyssen (Author), Matthias DâHondt (Author), Valentijn Vergote (Author), Herwig Jansen (Author), Christian Burvenich (Author), Bart De Spiegeleer (Author)
• Format: Book
• Published: Elsevier, 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A highly selective and stability-indicating HPLC-method, combined with appropriate sample preparation steps, is developed for β-artemether assay and profiling of related impurities, including possible degradants, in a complex powder for oral suspension. Following HPLC conditions allowed the require...