Chlamydial infection in gynecology: the modern trends of the pathogenesis of diagnosis and treatment
Chlamydia infection (CI) continues to be one of the most common sexually transmitted infections in the gynecological practice. The analytical data indicates an increase in the incidence of CI despite the availability of diagnostic tests and screenings. Fundamental studies in recent years have allowe...
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| Format: | Book |
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IP Berlin A.V.,
2013-04-01T00:00:00Z.
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| Summary: | Chlamydia infection (CI) continues to be one of the most common sexually transmitted infections in the gynecological practice. The analytical data indicates an increase in the incidence of CI despite the availability of diagnostic tests and screenings. Fundamental studies in recent years have allowed to clarify the problems of susceptibility to CI, as well as to establish the role of gene mutations in long term complications emergence in women. Nucleic acid amplification methods (SIA) improvement of has led to the possibility of collecting the material by patients themselves which, in the coming years can completely change the current system of screening. Russian IASC by remaining inexpensive are still able to match the commercial demands of the foreign test system in terms of sensitivity and specificity. Mutations in the loci of plasmid DNA of Chlamydia can lead to false-negative results of the IASC. Azithromycin, due to its unique pharmacodynamic properties, is most commonly used in the treatment of CI in Russia and abroad. The drug proved to be safe and effective in pregnancy. The results of post-therapeutic screenings indicate the need of increasing the drug dose. Clinical studies have confirmed its efficacy in the PID. |
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| Item Description: | 2079-5696 2079-5831 |