Mucosal immunization with a flagellin-adjuvanted Hgp44 vaccine enhances protective immune responses in a murine Porphyromonas gingivalis infection model

• Main Authors: Sao Puth (Author), Seol Hee Hong (Author), Mi Jin Park (Author), Hye Hwa Lee (Author), Youn Suhk Lee (Author), Kwangjoon Jeong (Author), In-Chol Kang (Author), Jeong Tae Koh (Author), Byounggon Moon (Author), Sang Chul Park (Author), Joon Haeng Rhee (Author), Shee Eun Lee (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic periodontitis is caused by interactions between the oral polymicrobial community and host factors. Periodontal diseases are associated with dysbiotic shift in oral microbiota. Vaccination against periodontopathic bacteria could be a fundamental therapeutic to modulate polymicrobial biofilms....