Dose Optimisation of Posaconazole and Therapeutic Drug Monitoring in Pediatric Patients

• Main Authors: Mengmeng Jia (Author), Qiwen Zhang (Author), Zifei Qin (Author), Dao Wang (Author), Peng Liu (Author), Jing Yang (Author), Xiaojian Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Experience in the clinical use of posaconazole (PCZ) in pediatric patients is limited, and no specific dose recommendations exist. This study aimed to investigate an appropriate dosing regimen, and assess the exposure-response relationships of PCZ in children. We reviewed the medical records of inpa...