Impact of Erythrocyte Duffy Antigen Genetic Polymorphism on the Distribution of GroB-T, a Novel Human CXC Chemokine

• Main Authors: Timothy W Hepburn (Author), LeeAnn P Tobia (Author), Wei Shi (Author), Timothy A McIntyre (Author), Charles B Davis (Author)
• Format: Book
• Published: Frontiers Media S.A., 2007-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose. GroB-T, a human CXC chemokine, has been studied for its potential to mobilize stem cells. Chemokines bind specifically to receptors on target immune cells but also to a homologous erythrocyte blood group antigen, the Duffy Antigen/Receptor for Chemokines (DARC) that is subject to genetic po...