Upregulation of Thioredoxin Reductase 1 Expression by Flavan-3-Ols Protects Human Kidney Proximal Tubular Cells from Hypoxia-Induced Cell Death

• Główni autorzy: Jixiao Zhu (Autor), Manqin Fu (Autor), Jian Gao (Autor), Guoyu Dai (Autor), Qiunong Guan (Autor), Caigan Du (Autor)
• Format: Książka
• Wydane: MDPI AG, 2022-07-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Renal hypoxia and its associated oxidative stress is a common pathway for the development of kidney diseases, and using dietary antioxidants such as flavan-3-ols to prevent kidney failure has received much attention. This study investigates the molecular mechanism by which flavan-3-ols prevent hypox...