Therapeutic Drug Monitoring of Tacrolimus Based on Volumetric Absorptive Microsampling Technique (VAMS) in Renal Transplant Pediatric Recipients-LC-MS/MS Method Development, Hematocrit Effect Evaluation, and Clinical Application

• Hauptverfasser: Arkadiusz Kocur (VerfasserIn), Dorota Marszałek (VerfasserIn), Jacek Rubik (VerfasserIn), Agnieszka Czajkowska (VerfasserIn), Tomasz Pawiński (VerfasserIn)
• Format: Buch
• Veröffentlicht: MDPI AG, 2023-01-01T00:00:00Z.
• Schlagworte: article
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Tacrolimus (TAC) is post-transplant pharmacotherapy's most widely used immunosuppressant. In routine clinical practice, frequent uncomfortable venipuncture is necessary for whole-blood (WB) collection to check trough TAC levels. Volumetric absorptive microsampling (VAMS) is an alternative strat...