Sodium-glucose co-transporter2 expression and inflammatory activity in diabetic atherosclerotic plaques: Effects of sodium-glucose co-transporter2 inhibitor treatment

• Main Authors: Nunzia D'Onofrio (Author), Celestino Sardu (Author), Maria Consiglia Trotta (Author), Lucia Scisciola (Author), Fabrizio Turriziani (Author), Franca Ferraraccio (Author), Iacopo Panarese (Author), Lella Petrella (Author), Mara Fanelli (Author), Piero Modugno (Author), Massimo Massetti (Author), Ludovica Vittoria Marfella (Author), Ferdinando Carlo Sasso (Author), Maria Rosaria Rizzo (Author), Michelangela Barbieri (Author), Fulvio Furbatto (Author), Fabio Minicucci (Author), Ciro Mauro (Author), Massimo Federici (Author), Maria Luisa Balestrieri (Author), Giuseppe Paolisso (Author), Raffaele Marfella (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: We evaluated sodium-glucose co-transporter2 (SGLT2) expression and the effect of SGLT2 inhibitor (SGLT2i) therapies on carotid plaques of asymptomatic diabetic and non-diabetic patients. Methods: Plaques were obtained from 296 non-diabetic patients and 227 patients with type 2 diabetes un...