Recent advances in the development of poly(ester amide)s-based carriers for drug delivery

Biodegradable and biocompatible biomaterials have several important applications in drug delivery. The biomaterial family known as poly(ester amide)s (PEAs) has garnered considerable interest because it exhibits the benefits of both polyester and polyamide, as well as production from readily availab...

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Bibliographic Details
Main Authors: Rui Xie (Author), Jiang Li (Author), Min Zhao (Author), Fan Wu (Author)
Format: Book
Published: Elsevier, 2024-07-01T00:00:00Z.
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100 1 0 |a Rui Xie  |e author 
700 1 0 |a Jiang Li  |e author 
700 1 0 |a Min Zhao  |e author 
700 1 0 |a Fan Wu  |e author 
245 0 0 |a Recent advances in the development of poly(ester amide)s-based carriers for drug delivery 
260 |b Elsevier,   |c 2024-07-01T00:00:00Z. 
500 |a 1319-0164 
500 |a 10.1016/j.jsps.2024.102123 
520 |a Biodegradable and biocompatible biomaterials have several important applications in drug delivery. The biomaterial family known as poly(ester amide)s (PEAs) has garnered considerable interest because it exhibits the benefits of both polyester and polyamide, as well as production from readily available raw ingredients and sophisticated synthesis techniques. Specifically, α-amino acid-based PEAs (AA-PEAs) are promising carriers because of their structural flexibility, biocompatibility, and biodegradability. Herein, we summarize the latest applications of PEAs in drug delivery systems, including antitumor, gene therapy, and protein drugs, and discuss the prospects of drug delivery based on PEAs, which provides a reference for designing safe and efficient drug delivery carriers. 
546 |a EN 
690 |a Poly(ester amide)s 
690 |a Biomaterials 
690 |a Drug delivery 
690 |a Gene vector 
690 |a Smart-responsive 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Saudi Pharmaceutical Journal, Vol 32, Iss 7, Pp 102123- (2024) 
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