Activation and Inhibition of Human Matrix Metalloproteinase-9 (MMP9) by HOCl, Myeloperoxidase and Chloramines
Matrix metalloproteinase-9 (MMP9, gelatinase B) plays a key role in the degradation of extracellular-matrix (ECM) proteins in both normal physiology and multiple pathologies, including those linked with inflammation. MMP9 is excreted as an inactive proform (proMMP9) by multiple cells, and particular...
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Main Authors: | Yihe Wang (Author), Christine Y. Chuang (Author), Clare L. Hawkins (Author), Michael J. Davies (Author) |
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Format: | Book |
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MDPI AG,
2022-08-01T00:00:00Z.
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